Artificial Kidney Research

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Preamble

Mid 2014 Sam went onto kidney dialysis. He was lucky it did not happen earlier. He had had indications of kidney problem 30 years before.
At first he was on peritoneal dialysis, but it did not work for him; by Nov 2014 he was on haemodialysis.

He is being treated in an excellent clinic in Lindfield, Sydney, Australia.
He is not eligible for a transplant because of other health problems.

Hence our interest in kidney research into wearable or implantable equipment, and any other relevant information.

This page aims to provide links to some of that information.

Latest information is highlighted in Bold

Disclaimer: this list in no way constitutes advice. All the information through the links is the responsibility of the publishers. Kidney research is about science. As knowledge advances, some previous certainties are discarded, new ones emerge. It takes longer than we would like.

November 2018, I last updated this page in February 2017. The 2 major research organisations in USA have taken much longer than they expected to reach their early research goals. Both have not chosen to raise monies in other countries. I am aware that both UK and Australia have arrangements whereby donations to suitable overseas charitable organsations may be eligible for tax deductions, if they have a local organisation.

I would appreciate comments on errors and ommissions, plus other leads. Email: harburgAToptusnet.com.au

Artificial kidney research websites & ancilliary information

Three ways to build an artificial kidney
June 2016
This site summarises the current state of research:
wearable, implantable, and bioartificial kidneys which could improve and extend patients' lives.

Wearable Artificial Kidney

Dr. Victor Gura is a nephrologist turned inventor, in Beverly Hills, California and is affiliated with Cedars-Sinai Medical Center.
He received his medical degree from University of Buenos Aires and has been in practice for more than 20 years.

Wearable Artificial Kidney gets green light for US trials
September 2014
This is the prototype which is referred to in the Medscape articles below

New Wearable Artificial Kidney Improves Mobility
New Orleans, February 2015

Wearable Artificial Kidney Potential Alternative to Dialysis
San Diego, November 2015

Wearable Artificial Kidney Offers Hope for Dialysis Patients
June 2016

Nephrology nursing and the wearable artificial kidney/
2016

Patient trial confirms Wearable Artificial Kidney proof of concept
June 2016
The above article refers to
A wearable artificial kidney for patients with end-stage renal disease
June 2016
This gives more detail

Third-generation wearable artificial kidney will be lighter, more discrete.

March 2018
Victor Gura, MD, said at the Annual Dialysis Conference that the wearable artificial kidney seeks "the ability to give the patients quality of life where they can walk around instead of being tethered to a machine for all those long hours and let them eat and drink to their heart's content."

Latest generation of the artificial wearable kidney is focused on quality of life

October 2018
A third-generation artificial kidney has the potential to provide unprecedented wearability and convenience, enable freedom from phosphate binders and excessive dietary restrictions and produce a significant cost savings.

Nanodialysis
Nanodialysis is bringing innovative products into the market of blood purification and dialysis based on nanostructured materials.
Page dated 2015
Nanodialysis artificial kidney examples/
Shows examples of portable haemodialysis, and wearable peritoneal dialysis
Page dated 2015

Major Step Towards Portable Artificial Kidney
Lausanne, Switzerland
May 2014
Debiotech of Switzerland, AWAK of Singapore and Neokidney Development, an initiative of the Dutch Kidney Foundation, have signed a joint venture agreement to complete a functional model in 2015. Clinical trials are planned for 2017. The portable artificial kidney will enable the frequent and longer home haemodialysis that significantly improves and extends patients' lives.
From them:
http://www.neokidney.nl/index.php/en/
Page 2017, in English
They are developing a small portable kidney which makes frequent haemodialysis possible at home or on the go
www.nierstichting.nl/
Dutch only
Group not informative yet

Implantable Artificial Kidney

Shuvo Roy, PhD, is a professor in the Department of Bioengineering and Therapeutic Sciences in the Schools of Pharmacy and Medicine, and technical director of The Kidney Project at UCSF, a multi-institutional collaboration. The Kidney Project team has prototyped and begun testing key components of the coffee-cup-sized device, which mimics functions of the human kidney. University of California, San Francisco

The Kidney Project
Creating a bioartificial kidney as a permanent solution to end stage renal disease
Undated

Implantable artificial kidney based on microchips sees major progress
February 2016

Artificial Kidney Research Advances Through UCSF Collaboration
November 2015

Artificial kidney will save millions of lives, scientists say
August 2015

Implantable artificial kidney offers economical alternative to dialysis
November 2015

Implantable artificial kidney developers working with patients on device development
Sept 2017
Clinical trials for the implantable artificial kidney haven't started yet, but the device's developers are already seeking feedback from patients. The device, currently in preclinical trials, uses microchip filters and living kidney cells that would be powered by a patient's own heart. It is being developed by the Kidney Project, (see Facebook below) a collaboration between the University of California at San Francisco and Vanderbilt University. In March, they announced a partnership with Home Dailyzors United (HDU), who will help provide education and support to patients, as well as seek feedback on preferences.

Facebook link
Links to The Kidney project postings.
Kidney Project
Home Page

Other Artificial Kidney Information

Accuron Technologies' medtech division invests into AWAK Technologies
December 2016
Funding will support the commercialization of AWAK Technologies' disruptive platform, targeting the US$85 billion end-stage renal disease market
The above article came via:
Home Dialysis Central, news about what is in the pipeline
Date Current, links to several interesting sources. Information constantly changing

3D-printed kidney technique enables transplant for 2 year old
January 2016

Researchers create a 'living kidney membrane'
April 2015

Replacement organs and tissues
August 2016
Included 3D printing a kidney

Wake Forest recycles "waste" kidneys into tailor-made replacements
October 2015
Full article:
Researchers work to build replacement kidneys in the lab/
June 2015

Dialysis device developed by Imperial team a step closer to patients
September 2015

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Updated November 2018